Despite setbacks and funding cuts — and a quieting of the hype blaring its arrival — multiple CRISPR-based trials are ...
Two recent studies identified gene knockouts that may make CAR T-cell therapy more effective, but the next step is applying the hypotheses in humans.
The power of CRISPR became definitively clear when the first CRISPR-based gene therapy, Casgevy (exa-cel), won regulatory approvals for the treatment of sickle cell disease. But CRISPR’s applications ...
Preclinical data presented at the European Society of Gene and Cell Therapy (ESGCT) highlight a potential best-in-class profile--The AATD ...
Researchers corrected lamin A gene mutations, preventing skeletal and cardiac abnormalities and extending mice lifespans.
CRISPR Therapeutics has developed SyNTase editing ... off-target effects. In a humanized mouse model, SyNTase editing components encapsulated in a lipid nanoparticle (LNP) enabled highly efficient, ...
CRISPR Therapeutics (CRSP) announced the acceptance of an abstract for oral presentation at the European Society of Gene and Cell Therapy, ESGCT, ...
Buildup of acidic byproducts in pancreatic tumors alleviates the effects of other environmental stresses and aids the cancer.
The influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.
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