DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers ...

Deinococcus radiodurans is renowned for its extraordinary resistance to ionising radiation and other environmental stresses. This bacterium employs a combination of passive and active mechanisms to ...

Researchers with McMaster University have discovered that the protein mutated in patients with Huntington's Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA ...

Naked mole-rats are one of nature's most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ...

The findings offer potential insights into why naked mole-rats exhibit remarkable resistance to a wide spectrum of ...