Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) and collaborating institutions have developed a DNA-editing method that introduces small chemical modifications at ...

DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

DNA has tremendous potential as a data storage medium, but the process of synthesizing DNA from scratch is time-consuming. It has to be done one nucleotide at a time in a specific sequence. New ...

In a January Science magazine story about his work, the word "heretic" is splashed in teal letters across the page. On those pages and elsewhere, he's been called a "maverick" and a "pioneer," winning ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now, researchers led by Xiaoqi Feng at the Institute of Science and Technology ...