From breaking down food to repairing tissues, enzymes are at the heart of nearly every bodily function. Enzymes are ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

GLP-1–pathway agonists such as semaglutide and newer multi-agonists have transformed care for obesity and diabetes, yet developers still wrestle with durability, tissue targeting, and signal "bias." ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Enzymes are biological catalysts that facilitate biochemical transformations. An international team of bioinformatics researchers has developed a new process for predicting Michaelis constants, which ...

Iridoids are a widespread and evolutionarily ancient class of plant secondary metabolites belonging to the terpenes. They ...

Scientists have found that the activity of proprotein covertases, the enzymes that turn-on proteins, is regulated by the location of the enzyme inside the cell. The study uses a novel biosensor, CLIP, ...

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