Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Our skin protects us from everyday mechanical stresses, like friction, cuts, and impacts. A key part of this ...

Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. Ablation of Bmp9 reduces cell proliferation and ...

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible for approximately half of all cases of hereditary hearing loss. Connexin 26 ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...