Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 15 (Jul. 22, 2003), pp. 8692-8697 (6 pages) The DnaA replication initiation protein has been shown to be ...
Many non-essential bacterial characteristics are encoded by plasmids, extrachromosomal genetic elements which exist in the cell predominantly as circular molecules of supercoiled double-stranded DNA.
The tumor suppressor protein p53 is emerging as a central regulator of homologous recombination (HR) processes and DNA replication. P53 may downregulate HR through multiple mechanisms including the ...
Plasmid DNA (pDNA) is a key material for producing gene therapies, mRNA and DNA vaccines. The alkaline lysis process to isolate pDNA is simple on the benchtop, but it’s challenging at industrial scale ...
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