EPFL researchers have uncovered how transcription factor dosage reshapes cell identity, showing that even small differences ...

Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein. CTCF is a critical protein known to play various roles in key biological ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children's Research Hospital have found direct ...

St. Jude Children’s Research Hospital scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer. CTCF is known by biologists for being a master ...

As microscopy tools get better and better, scientists have been able to visualize structures on a smaller and smaller scale. Researchers have now been able to capture an enzyme called RNA polymerase ...

Biological rhythms aren't just for sleep. In the tiny worm C. elegans, researchers in the Grosshans lab and the Computational ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can ...

The Wilkinson laboratory studies reverse transcriptases and retrotransposons using biochemistry, structural biology, and genome mining.

(Memphis, Tenn.—January 25, 2023) CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children’s Research Hospital used a ...